The consortium is comprised of 18 leading organizations from 5 different countries with a vast background and expertise in the technologies to be developed and implemented:
Genomic and clinical data generation
Ethical and legal issues regarding genomic and clinical data sharing
Data Management
Genomic and clinical data analysis and pipeline benchmarking
Develop software for storing, indexing and querying genomic data collected by each EUCANCan node
Develop a high-speed file transfer service for efficient exchange of clinical and genomic data files among EUCANCan nodes, accessible to authorized users
Develop software to extract and uniformly annotate genomic variants identified by EUCANCan nodes
To define a circuit for long-term raw data and metadata storage and flow, as well as access protocols
To prepare global infrastructures and facilitate deployment of local infrastructures for the long-term storage and flow of raw data
To synchronize connectivity and interoperability protocols to interact within EUCANCan system at the level of genomic variant and clinical and phenotypical information
To adapt these infrastructures to local and national needs in healthcare systems
Deploy, refine and develop automated tools and annotation to filter and prioritise both germline and somatic alterations to support decision making in tumour boards
Contribution to pipeline development including for cloud pipelines
Develop a policy framework to enable international transfer of personal data in the framework of the project, in accordance with European and Canadian Law and regulations
Provide tools for harmonized legal compliance as a prototype for future research efforts to address common diseases
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