The overall strategy of the project was only possible with the appropriate ethical and legal advising from experts in the topic. MCG, UPV/EHU and HdAW were involved in several genomic and clinical initiatives, such as ICGC, assuring the accomplishment of WP6 objectives, which aimed at assessing the sharing of genomic and clinical data across borders. WP6 was connected with WPs 1 through 5, as it was required to map and identify the data life cycle of the health data involved in the system and to identify ethico-legal considerations that arose in the data-sharing workflows. WP5 served as a direct use case for the development of prototype tools for legal compliance in research collaborations beyond human genome oncology.