WP4 will work to (1) install a toolset in each EUCANCan node to index genomic data files and publish the metadata that describes these files to the Internet; (2) develop a metadata browser allowing researchers to discover EUCANCan-produced clinical/genomic data sets; (3) develop a service to be installed on each EUCANCan node to initiate a file transfer of a selected set of genomic files and their associated metadata; (4) informed by WP2, implement a uniform software pipeline for annotating the nature and functional impact of somatic and germline variants identified by genomic and transcriptomic sequencing; and (5) provide metadata search.