This cooperative framework is not only expected to immediately contribute to improve biomedical research in cancer, but to also serve as a model for globalizing and enriching Personalized Medicine initiatives, allowing the exchange of data, clinical experience and information across different national health systems.
EUCANCan builds on previous work performed by members of the consortium and related projects to align and interconnect existing European and Canadian infrastructures for the analysis and management of genomic oncology data. The EUCANCan network will be composed of reference nodes in Amsterdam, Barcelona, Berlin, Heidelberg, Paris and Toronto which have established strong research and clinical programs in the field of genomic oncology.
These reference nodes will work together in a federated and interoperable fashion to provide the genomic oncology community with a uniform computing environment for the processing, harmonization and secure sharing of cancer genome and phenome data in the context of clinical research, enabling the discovery of clinically-relevant patterns of genomic variation in cancer, such as biomarkers predictive of therapeutic response. This infrastructure will also provide a proving ground for federated genome analysis systems that may one day be integrated into national and regional healthcare systems.